Epilepsy: Models, Mechanisms and Concepts

Advances in epilepsy research are occurring at a rapid rate, resulting in a bewildering wealth of data. The implications of this knowledge for future research and clinical practice can be confusing. This volume concentrates on the concepts and models of epilepsy which have been developed as a result of this research. Written by prominent researchers in the field, this book presents a number of major concepts and hypotheses through which epilepsy research has been advanced. Chapters focus on the pathways and mechanisms through which seizure activity is initiated and spread, in both normal and abnormal brain tissues, and discuss the special properties of epileptogenesis in the immature brain. In a field in which rapid advances lead to constant update of empirical data, this book takes a conceptual approach to the subject and provides a solid framework within which to understand the emerging issues. It will be relevant to basic neuroscientists, neurologists and neurosurgeons.